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Are there any side effects of drinking sarsaparilla soda?

Quick answer

Sarsaparilla soda is a soft drink flavored with sarsaparilla, so most of its effects come from sugar and other ingredients rather than the herb. Sarsaparilla as a supplement can cause stomach upset and increased urination, and PeaceHealth advises against it during pregnancy or breastfeeding. Ask a health professional if you take medicine, especially digoxin or water pills.

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In this article
  1. Does sarsaparilla soda have side effects?
  2. What are the known effects of the herb?
  3. Who should be careful?
  4. What about the soda itself?

Does sarsaparilla soda have side effects?

For most healthy adults, a can of sarsaparilla soda is like any sweet soft drink. The main drawbacks are sugar and, for some people, stomach upset. Most research on sarsaparilla is about the root as a supplement, not the soda, and the pages we read do not give safety information for sarsaparilla soda specifically. WebMD says the FDA considers sarsaparilla a natural flavoring for foods and drinks.

What are the known effects of the herb?

  • WebMD lists an increased need to urinate and an upset stomach as the most common side effects, and notes that serious allergic reactions are rare but can happen.
  • PeaceHealth cites a German monograph reporting possible stomach upset and short-term kidney irritation.

Who should be careful?

  • Pregnant or breastfeeding: PeaceHealth says sarsaparilla should not be taken during pregnancy or breastfeeding, and WebMD says it is not known to be safe.
  • Kidney or liver problems: WebMD advises talking to a provider first.
  • People on diuretics (water pills): WebMD says to discuss it with your provider.
  • People taking digoxin: PeaceHealth lists a potential interaction.
  • Allergy to sarsaparilla or Smilax plants.

What about the soda itself?

  • Check the label: sugar, caffeine and flavoring vary by brand. Many sarsaparilla sodas use artificial flavoring rather than the root, so the herb dose may be tiny, but this is not measured on the pages we read.
  • Large amounts of any sugary soda are a poor choice for teeth and weight.

The FDA has not reviewed sarsaparilla supplements for safety and effectiveness. This page is general information, not medical advice; ask your doctor or pharmacist about your own situation.

People also ask

Is sarsaparilla soda safe to drink?

For most healthy adults an occasional can is like any soft drink. People who are pregnant, breastfeeding, have kidney or liver problems or take certain medicines should ask a health professional first.

Does sarsaparilla soda contain caffeine?

It depends on the brand. Read the label.

Can sarsaparilla make you urinate more?

WebMD lists an increased need to urinate as a common effect of the herb. How much a soda contributes is not established.

General information only, not medical advice. If you have a health condition or are pregnant, ask your doctor before changing what you drink.

Sources

  1. WebMD: Sarsaparilla, read 5 Nov 2026
  2. PeaceHealth: Sarsaparilla, read 5 Nov 2026
Written by Drinks Type Editorial Team · Published Nov 26, 2024 · Updated Nov 5, 2026
About · How we verify this · Editorial policy · Corrections

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